Passionate about structural bioinformatics, molecular modeling, molecular dynamics, and 3D visualization, I am currently a CNRS Researcher (CRCN) at the I2BC Institute (Institute for Integrative Biology of the Cell), in the IMAPP Team. My research focuses on molecular modeling and molecular dynamics simulations of viral proteins (Hepatitis E, Hepatitis C, Norovirus) and their interactions with themselves, human proteins and biological membranes (working a lot with AlphaFold2, AlphaFold3 and derivates).

Previously, I worked in Nathalie Reuter’s group at the University of Bergen, where I studied the membrane-binding sites of peripheral membrane proteins.
I also held a postdoctoral position at the Servier Research Institute, developing new methods to expand their 3D bioisosteric fragment library.

During my Ph.D., under the supervision of Dr. Stéphane Bressanelli and Dr. Yves Boulard at the French Atomic Energy Commission (CEA, Paris-Saclay), I investigated Norovirus capsid self-assembly using molecular dynamics, homology modeling, protein-protein docking, and SAXS data acquisition and interpretation (see more at Norovirus Capsid Assembly).

During my Ph.D., I also taught in the Bioinformatics Master of Diderot University (Paris VII), mainly Python, Unix, Biostatistics, and visualization software… Several documents for students are accessible on this page.

You will find on my website all my professional content such as my CV (on the resume page), research projects, personal projects, publications, some tutorial and a gallery presenting my work.

This website aims to present me, my work and my lab. So don’t hesitate to contact me (thibault [dot] tubiana [at] i2bc [dot] paris-saclay [dot] fr) if you need more information, collaboration, documents…